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KMID : 0931320130130010069
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대한상부위장관.헬리코박터학회지
2013 Volume.13 No. 1 p.69 ~ p.72
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Upper Gastrointestinal Hemorrhage from Esophageal Ulcer Caused by Coinfection of Herpes Simplex Virus and Cytomegalovirus in Immunocompromised Patient
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Chung Heo-Hoon
Jang Jae-Young
Byun Ja-Min
Park Sun-Hee
Kim Dong-Hyun
Chang Young-Woon
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Abstract
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Coinfection with herpes simplex virus and cytomegalovirus is a very rare cause of esophageal ulcer and upper gastrointestinal hemorrhage. A 26 year-old male kidney transplant recipient was referred with a complaint of melena. Upper gastrointestinal endoscopy showed a huge esophageal ulcer in the anastomosis site of the esophagogastrostomy. The ulcer occupied about two-thirds of the circumference of the esophageal lumen and an exposed vessel in the ulcer base was noted. Pathologic findings with immunohistochemical stain showed co-infection of herpes simplex virus and cytomegalovirus. He was treated successfully with endoscopic hemostasis and antiviral therapy. We report a case of upper gastrointestinal hemorrhage from esophageal ulcer caused by coinfection of herpes simplex virus and cytomegalovirus.
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KEYWORD
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Esophageal ulcer, Simplexvirus, Cytomegalovirus, Gastrointestinal hemorrhage, Immunocompromised host
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